January 13, 2024

Diet       Part Two        

Lets talk the science of this drug and get terms right:

Google “What is a GLP-1 drug” and this is what you’ll see:  A GLP-1 drug is a glucagon-like peptide-1 receptor agonistwhich is a type of medication used to treat type 2 diabetes. A GLP-1 drug works by stimulating the pancreas to produce more insulin and reducing the amount of glucose released by the liver. A GLP-1 drug can also help with weight loss and improve heart and kidney health.

That’s the science. There is a class of drug called GLP-1 that was found to help type 2 diabetics. In doing that, this same drug was found to help with weight loss because it also decreased the desire for food. Well, once that fact got got you can image what happened next. Yes, products were quickly developed, named, and brought to market. The European drug maker Noro Nordisk (NVO) was the first out of the gate with 2 unique branded products: Ozempic to treat Diabetes and Wegovy to treat weight loss. Not to be beat out of any profits, the US company Eli Lilly developed and branded Mounjaro for Diabetes and Zepbound for weight loss.

Zepbound was the drug Oprah injected to lose her weight. The drug was not yet approved for that use but who’s going to say Oprah did wrong. On November 23, 2023, Zepbound was approved and Weight Watchers International kinda pivoted their strategy from counting points to sticking a needle in your stomach. I guess there is no longer a reason for the ladies to get together weekly and cheer each other on, ya think? But Eli Lilly as any red blooded American company would do, made their drugs BETTER than the others. Yes, they have studies (very recent studies) that show you’ll lose MORE weight on Zepbound versus Wegovy or Ozempic. But Ozempic has got that catchy commercial with the slogan and all. Anyway, that’s the Science and the Market thus far.

The downside is perhaps made evident by a Tweet I copied yesterday: “Several people I know on Ozempic all complained that Chick Fil A does not taste good anymore. Some other fun foods as well, but the fried chicken from there specifically was mentioned. And they all tried it over and over again with same results. Like, why would you keep trying?” Think about that for a minute…….

Cost is $1000 a month. Will insurance cover? How much? If you stop injecting the drug, the weigh will slowly return.  Think about THAT too.

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